|
Symbol Name ID |
Itpa
inosine triphosphatase (nucleoside triphosphate pyrophosphatase) MGI:96622 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgE level |
Epistaxis |
Joint hemorrhage |
Persistent bleeding after trauma |
Bruising susceptibility |
Petechiae |
Abnormal megakaryocyte morphology |
Increased megakaryocyte colony forming unit count |
Reduced erythrocyte adenylate kinase activity |
Reticulocytosis |
Hemolytic anemia |
Anemia of inadequate production |
Poikilocytosis |
Acanthocytosis |
Leukocytosis |
Acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Thrombocytopenia |
Congenital thrombocytopenia |
Intermittent thrombocytopenia |
Abnormal platelet shape |
Abnormal platelet volume |
Decreased mean platelet volume |
Lymphoma |
Elevated erythrocyte sedimentation rate |
| Disease(s) Associated with ITPA | ||||||||||||||||||||||||||
| acute lymphoblastic leukemia | ||||||||||||||||||||||||||
| hemolytic anemia | ||||||||||||||||||||||||||
| rheumatoid arthritis | ||||||||||||||||||||||||||
| thrombocytopenia |
| Mouse Phenotypes | extramedullary hematopoiesis |
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| Availability | Mouse Genotype | |
| Itpatm1Skmi/Itpatm1Skmi | ||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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